HUS1B Back

HUS1 checkpoint homolog b (S. pombe)

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NCBI Description of HUS1B
The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Community Annotation of HUS1B Add / Edit HUS1B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HUS1B is highly significantly mutated in
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HUS1B is significantly mutated in
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HUS1B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HUS1B