HTR7 Back

5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)

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NCBI Description of HTR7

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.

Community Annotation of HTR7 Add / Edit HTR7: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HTR7 is highly significantly mutated in
HTR7 is significantly mutated in
HTR7 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HTR7