HTR4 Back

5-hydroxytryptamine (serotonin) receptor 4

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NCBI Description of HTR4
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HTR4 is highly significantly mutated in
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HTR4 is significantly mutated in
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HTR4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HTR4