HTR3E Back

5-hydroxytryptamine (serotonin) receptor 3, family member E

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NCBI Description of HTR3E

This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HTR3E is highly significantly mutated in
HTR3E is significantly mutated in
HTR3E is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HTR3E