HSPA8 Back

heat shock 70kDa protein 8

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NCBI Description of HSPA8
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of HSPA8 Add / Edit HSPA8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HSPA8 is highly significantly mutated in
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HSPA8 is significantly mutated in
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HSPA8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HSPA8