HSPA5 Back

heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

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NCBI Description of HSPA5

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

Community Annotation of HSPA5 Add / Edit HSPA5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HSPA5 is highly significantly mutated in
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HSPA5 is significantly mutated in
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HSPA5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for HSPA5