HSP90B1 Back

heat shock protein 90kDa beta (Grp94), member 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HSP90B1

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Community Annotation of HSP90B1 Add / Edit HSP90B1: Annotations

No community annotations yet for HSP90B1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HSP90B1 is highly significantly mutated in
HSP90B1 is significantly mutated in
HSP90B1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HSP90B1