HSP90B1 Back

heat shock protein 90kDa beta (Grp94), member 1

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NCBI Description of HSP90B1
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Community Annotation of HSP90B1 Add / Edit HSP90B1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HSP90B1 is highly significantly mutated in
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HSP90B1 is significantly mutated in
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HSP90B1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HSP90B1