HSF1 Back

heat shock transcription factor 1

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NCBI Description of HSF1

The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.

Community Annotation of HSF1 Add / Edit HSF1: Annotations

No community annotations yet for HSF1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HSF1 is highly significantly mutated in
HSF1 is significantly mutated in
HSF1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HSF1