HSD17B12 Back

hydroxysteroid (17-beta) dehydrogenase 12

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NCBI Description of HSD17B12

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation.

Community Annotation of HSD17B12 Add / Edit HSD17B12: Annotations

No community annotations yet for HSD17B12.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HSD17B12 is highly significantly mutated in
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HSD17B12 is significantly mutated in
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HSD17B12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for HSD17B12