HS3ST4 Back

heparan sulfate (glucosamine) 3-O-sulfotransferase 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HS3ST4
This gene encodes the enzyme heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4. This enzyme generates 3-O-sulfated glucosaminyl residues in heparan sulfate. Cell surface heparan sulfate is used as a receptor by herpes simplex virus type 1 (HSV-1), and expression of this gene is thought to play a role in HSV-1 pathogenesis. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.

Community Annotation of HS3ST4 Add / Edit HS3ST4: Annotations

No community annotations yet for HS3ST4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HS3ST4 is highly significantly mutated in
(none)
HS3ST4 is significantly mutated in
(none)
HS3ST4 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HS3ST4