HRH4 Back

histamine receptor H4

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NCBI Description of HRH4
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of HRH4 Add / Edit HRH4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HRH4 is highly significantly mutated in
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HRH4 is significantly mutated in
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HRH4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HRH4