hippocalcin-like 1

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NCBI Description of HPCAL1

The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.

Community Annotation of HPCAL1 Add / Edit HPCAL1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HPCAL1 is highly significantly mutated in
HPCAL1 is significantly mutated in
HPCAL1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HPCAL1