HOXD9 Back

homeobox D9

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HOXD9

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.

Community Annotation of HOXD9 Add / Edit HOXD9: Annotations

No community annotations yet for HOXD9.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HOXD9 is highly significantly mutated in
HOXD9 is significantly mutated in
HOXD9 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HOXD9