HOXC11 Back

homeobox C11

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HOXC11
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

Community Annotation of HOXC11 Add / Edit HOXC11: Annotations

No community annotations yet for HOXC11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HOXC11 is highly significantly mutated in
(none)
HOXC11 is significantly mutated in
(none)
HOXC11 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HOXC11