HOOK2 Back

hook homolog 2 (Drosophila)

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NCBI Description of HOOK2
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HOOK2 is highly significantly mutated in
(none)
HOOK2 is significantly mutated in
(none)
HOOK2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HOOK2