HOMER2 Back

homer homolog 2 (Drosophila)

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NCBI Description of HOMER2
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HOMER2 is highly significantly mutated in
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HOMER2 is significantly mutated in
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HOMER2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HOMER2