HNRNPA2B1 Back

heterogeneous nuclear ribonucleoprotein A2/B1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HNRNPA2B1

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.

Community Annotation of HNRNPA2B1 Add / Edit HNRNPA2B1: Annotations

No community annotations yet for HNRNPA2B1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HNRNPA2B1 is highly significantly mutated in
(none)
HNRNPA2B1 is significantly mutated in
(none)
HNRNPA2B1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for HNRNPA2B1