NCBI Description of HK2
|Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.|
Community Annotation of HK2 Add / Edit HK2: Annotations
No community annotations yet for HK2.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.