HIST3H2BB Back

histone cluster 3, H2bb

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HIST3H2BB
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

Community Annotation of HIST3H2BB Add / Edit HIST3H2BB: Annotations

No community annotations yet for HIST3H2BB.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HIST3H2BB is highly significantly mutated in
(none)
HIST3H2BB is significantly mutated in
(none)
HIST3H2BB is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HIST3H2BB