NCBI Description of HIST1H2BD
|Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3.|
Community Annotation of HIST1H2BD Add / Edit HIST1H2BD: Annotations
No community annotations yet for HIST1H2BD.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.