HIGD1B Back

HIG1 domain family, member 1B

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NCBI Description of HIGD1B

This gene encodes a member of the hypoxia inducible gene 1 (HIG1) domain family. The encoded protein is localized to the cell membrane and has been linked to tumorigenesis and the progression of pituitary adenomas. Alternative splicing results in multiple transcript variants.

Community Annotation of HIGD1B Add / Edit HIGD1B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HIGD1B is highly significantly mutated in
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HIGD1B is significantly mutated in
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HIGD1B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for HIGD1B