HIC1 Back

hypermethylated in cancer 1

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NCBI Description of HIC1

This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of HIC1 Add / Edit HIC1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HIC1 is highly significantly mutated in
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HIC1 is significantly mutated in
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HIC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for HIC1