HERC1 Back

hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1

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NCBI Description of HERC1

This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes.

Community Annotation of HERC1 Add / Edit HERC1: Annotations

No community annotations yet for HERC1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HERC1 is highly significantly mutated in
HERC1 is significantly mutated in
HERC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HERC1