hepatocyte cell adhesion molecule

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NCBI Description of HEPACAM

The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.

Community Annotation of HEPACAM Add / Edit HEPACAM: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HEPACAM is highly significantly mutated in
HEPACAM is significantly mutated in
HEPACAM is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HEPACAM