HELLS Back

helicase, lymphoid-specific

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NCBI Description of HELLS
This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Community Annotation of HELLS Add / Edit HELLS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HELLS is highly significantly mutated in
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HELLS is significantly mutated in
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HELLS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HELLS