HECTD3 Back

HECT domain containing 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HECTD3
The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of HECTD3 Add / Edit HECTD3: Annotations

No community annotations yet for HECTD3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HECTD3 is highly significantly mutated in
(none)
HECTD3 is significantly mutated in
(none)
HECTD3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HECTD3