HDGF Back

hepatoma-derived growth factor (high-mobility group protein 1-like)

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NCBI Description of HDGF
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of HDGF Add / Edit HDGF: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HDGF is highly significantly mutated in
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HDGF is significantly mutated in
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HDGF is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HDGF