HCRTR1 Back

hypocretin (orexin) receptor 1

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NCBI Description of HCRTR1
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HCRTR1 is highly significantly mutated in
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HCRTR1 is significantly mutated in
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HCRTR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HCRTR1