HAS3 Back

hyaluronan synthase 3

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NCBI Description of HAS3
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.

Community Annotation of HAS3 Add / Edit HAS3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HAS3 is highly significantly mutated in
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HAS3 is significantly mutated in
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HAS3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HAS3