HAO2 Back

hydroxyacid oxidase 2 (long chain)

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NCBI Description of HAO2
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described.

Community Annotation of HAO2 Add / Edit HAO2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HAO2 is highly significantly mutated in
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HAO2 is significantly mutated in
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HAO2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HAO2