GUK1 Back

guanylate kinase 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GUK1
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of GUK1 Add / Edit GUK1: Annotations

No community annotations yet for GUK1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GUK1 is highly significantly mutated in
(none)
GUK1 is significantly mutated in
(none)
GUK1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GUK1