GUCY1A3 Back

guanylate cyclase 1, soluble, alpha 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GUCY1A3

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Community Annotation of GUCY1A3 Add / Edit GUCY1A3: Annotations

No community annotations yet for GUCY1A3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GUCY1A3 is highly significantly mutated in
(none)
GUCY1A3 is significantly mutated in
(none)
GUCY1A3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GUCY1A3