GTSE1 Back

G-2 and S-phase expressed 1

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NCBI Description of GTSE1
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Community Annotation of GTSE1 Add / Edit GTSE1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GTSE1 is highly significantly mutated in
(none)
GTSE1 is significantly mutated in
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GTSE1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GTSE1