GTPBP3 Back

GTP binding protein 3 (mitochondrial)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GTPBP3

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Community Annotation of GTPBP3 Add / Edit GTPBP3: Annotations

No community annotations yet for GTPBP3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GTPBP3 is highly significantly mutated in
(none)
GTPBP3 is significantly mutated in
(none)
GTPBP3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GTPBP3