GTF3C3 Back

general transcription factor IIIC, polypeptide 3, 102kDa

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NCBI Description of GTF3C3

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of GTF3C3 Add / Edit GTF3C3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GTF3C3 is highly significantly mutated in
GTF3C3 is significantly mutated in
GTF3C3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GTF3C3