GTF2IRD2B Back

GTF2I repeat domain containing 2B

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NCBI Description of GTF2IRD2B

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif, two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors, one CHARLIE8 transposable element-like sequence, and a BED zinc finger. This gene lies within a region that is deleted in Williams-Beuren syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Community Annotation of GTF2IRD2B Add / Edit GTF2IRD2B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GTF2IRD2B is highly significantly mutated in
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GTF2IRD2B is significantly mutated in
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GTF2IRD2B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GTF2IRD2B