GTF2A1 Back

general transcription factor IIA, 1, 19/37kDa

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NCBI Description of GTF2A1
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010].

Community Annotation of GTF2A1 Add / Edit GTF2A1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GTF2A1 is highly significantly mutated in
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GTF2A1 is significantly mutated in
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GTF2A1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GTF2A1