GSTO1 Back

glutathione S-transferase omega 1

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NCBI Description of GSTO1
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of GSTO1 Add / Edit GSTO1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GSTO1 is highly significantly mutated in
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GSTO1 is significantly mutated in
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GSTO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GSTO1