GSTK1 Back

glutathione S-transferase kappa 1

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NCBI Description of GSTK1
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.

Community Annotation of GSTK1 Add / Edit GSTK1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GSTK1 is highly significantly mutated in
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GSTK1 is significantly mutated in
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GSTK1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GSTK1