GSDMB Back

gasdermin B

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NCBI Description of GSDMB
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Community Annotation of GSDMB Add / Edit GSDMB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GSDMB is highly significantly mutated in
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GSDMB is significantly mutated in
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GSDMB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GSDMB