GRIK4 Back

glutamate receptor, ionotropic, kainate 4

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NCBI Description of GRIK4
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GRIK4 is highly significantly mutated in
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GRIK4 is significantly mutated in
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GRIK4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GRIK4