GRIK4 Back

glutamate receptor, ionotropic, kainate 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GRIK4

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.

Community Annotation of GRIK4 Add / Edit GRIK4: Annotations

No community annotations yet for GRIK4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GRIK4 is highly significantly mutated in
GRIK4 is significantly mutated in
GRIK4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GRIK4