GRHPR Back

glyoxylate reductase/hydroxypyruvate reductase

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NCBI Description of GRHPR
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.

Community Annotation of GRHPR Add / Edit GRHPR: Annotations

No community annotations yet for GRHPR.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GRHPR is highly significantly mutated in
(none)
GRHPR is significantly mutated in
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GRHPR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GRHPR