GRHL2 Back

grainyhead-like 2 (Drosophila)

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NCBI Description of GRHL2

The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.

Community Annotation of GRHL2 Add / Edit GRHL2: Annotations

No community annotations yet for GRHL2.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GRHL2 is highly significantly mutated in
GRHL2 is significantly mutated in
GRHL2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GRHL2