GREB1 Back

growth regulation by estrogen in breast cancer 1

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NCBI Description of GREB1

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of GREB1 Add / Edit GREB1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GREB1 is highly significantly mutated in
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GREB1 is significantly mutated in
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GREB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GREB1