GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

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NCBI Description of GRASP

This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.

Community Annotation of GRASP Add / Edit GRASP: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GRASP is highly significantly mutated in
GRASP is significantly mutated in
GRASP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GRASP