GPT2 Back

glutamic pyruvate transaminase (alanine aminotransferase) 2

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NCBI Description of GPT2

This gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of GPT2 Add / Edit GPT2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GPT2 is highly significantly mutated in
GPT2 is significantly mutated in
GPT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GPT2