GPS1 Back

G protein pathway suppressor 1

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NCBI Description of GPS1
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of GPS1 Add / Edit GPS1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPS1 is highly significantly mutated in
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GPS1 is significantly mutated in
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GPS1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GPS1