GPR98 Back

G protein-coupled receptor 98

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NCBI Description of GPR98

This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.

Community Annotation of GPR98 Add / Edit GPR98: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR98 is highly significantly mutated in
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GPR98 is significantly mutated in
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GPR98 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GPR98