GPR78 Back

G protein-coupled receptor 78

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GPR78
The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of GPR78 Add / Edit GPR78: Annotations

No community annotations yet for GPR78.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR78 is highly significantly mutated in
(none)
GPR78 is significantly mutated in
(none)
GPR78 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GPR78