GPR50 Back

G protein-coupled receptor 50

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NCBI Description of GPR50
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR50 is highly significantly mutated in
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GPR50 is significantly mutated in
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GPR50 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GPR50